Table 4.

Searching Promoters for Genes with Known 5′ ESTs

Programs Training set of 102 promoters Test set of 110 promoters
true prediction (sensitivity) false prediction (FP/All P) undetected true prediction (sensitivity) false prediction (FP/All P) undetected
PROSCAN1.7 25 (25%)17 (40%)7518 (16%)25 (58%)78
NNPP2.0 41 (40%)46 (53%)3120 (18%)71 (78%)30
PromFD1.0 47 (46%)45 (49%)4842 (38%)52 (55%)47
promoter2.0 5 (5%)92 (95%)58 (7%)86 (91%)16
TSSG 52 (51%)13 (20%)3733 (30%)32 (49%)45
TSSW 35 (34%)28 (44%)3931 (28%)41 (57%)38
CONPRO 59 (58%)7 (11%)3941 (37%)7 (15%)62

[i] CONPRO can find promoters for about 37% human genes. Of all the predictions made by CONPRO, about 85% are correct. Additional information is given in the legend of Table 1.