Table 4.

Thyroid Hormone–Induced Up-Regulation of mRNA Expression for Genes of Protein Catabolism

UniGene no. Encoded protein Fold
Hs.9280Proteasome (prosome, macropain) subunit, β type, 93.20
Hs.61153Proteasome (prosome, macropain) 26S subunit, ATPase, 22.56
Hs.79137Protein-l-isoaspartate (d-aspartate)O-methyltransferase2.15
Hs.811Ubiquitin-conjugating enzyme E2B (RAD6 homolog)2.14
Hs.77578Ubiquitin-specific protease 9, X chromosome2.10
Hs.79357Proteasome (prosome, macropain) 26S subunit, ATPase, 62.06
Hs.82159Proteasome (prosome, macropain) subunit, α type, 12.04
Hs.4295Proteasome (prosome, macropain) 26S subunit, non-ATPase, 122.02
Hs.12272Beclin-11.95
Hs.76913Proteasome (prosome, macropain) subunit, α type, 51.93
Hs.251531Proteasome (prosome, macropain) subunit, α type, 41.88
Hs.86978Prolyl endopeptidase1.87
Hs.78950Branched chain keto acid dehydrogenase E1, α polypeptide1.85
Hs.167108Proteasome (prosome, macropain) subunit, α type, 31.83
Hs.99819Ubiquitin-specific protease 161.81
Hs.82919Cullin 21.79
Hs.75981Ubiquitin-specific protease 14 (tRNA-guanine transglycosylase)1.74
Hs.79357Proteasome (prosome, macropain) 26S subunit, ATPase, 61.68
Hs.15303Protein similar to mouse ubiquitin-protein ligase E3-α1.66
Hs.101408Branched chain aminotransferase 2, mitochondrial1.55

[i] The fold increase represents the mean of the five comparisons.