Table 4.

Phylogenetic Footprinting Results for the Study Set Using Orthologous Data from Multiple Species

Number of motif predictions Correspondence with known sites Motif predictions with avg MAP ≥ critical value Correspondence with known sites for:
Motif predictions with avg MAP ≥ critical value Motif predictions with avg MAP < critical value
EC-ST-YP-VC-HI-SO-PA:
 Predictions with ≥2 species16368.7% (112/163)52.1% (85/163)75.3% (64/85)61.5% (48/78)
 Predictions with ≥3 species11674.1% (86/116)60.3% (70/116)80.0% (56/70)65.2% (30/46)
 Predictions with ≥4 species8475.0% (63/84)69.0% (58/84)79.3% (46/58)65.4% (17/26)
EC-YP-VC-HI-SO-PA:
 Predictions with ≥2 species14067.9% (95/140)53.6% (75/140)84.0% (63/75)49.2% (32/65)
 Predictions with ≥3 species10265.7% (67/102)60.8% (62/102)85.5% (53/62)35.0% (14/40)
 Predictions with ≥4 species6569.2% (45/65)69.2% (45/65)84.4% (38/45)35.0% (7/20)

[i] MAP indicates maximum a posteriori probability; EC,Escherichia coli; ST, Salmonella typhi; YP,Yersinia pestis; VC, Vibrio cholerae; HI,Haemophilus influenzae; SO, Shewanella oneidensis; PA, Pseudomonas aeruginosa; BU,Buchnera sp.; AF, Acidithiobacillus ferrooxidans;and XF, Xylella fastidiosa.