Table 4.

Correlation of CpG Islands Filtered by Predicted Promoter Regions with Gene Annotation on Human Chromosome 22

CpG Islands correlated with PromoterInspector regions 358 (100%)
Gene group # abs.[v] rel. O
All genes54517047.5%6.8
Known genes24710529.5%11.5
Related genes150298.1%5.4
Predicted genes1484111.4%3.7
Pseudo genes13420.5%0.4
Additional predictions18651.8%

[i] (#) Number of annotated genes.

[ii] (abs) Absolute number of predicted promoter regions that were found near annotated genes.

[iii] (rel) Percentage of predicted promoter regions that were found near annotated genes.

[iv] (O) X-fold overrepresentation, i.e., number of predicted promoter predictions that were found near annotated genes divided by the number that would be expected to be located near these genes if the same number of positions were distributed randomly across the chromosome.

[v] Due to a small number of double scoring regions (a region is scored twice if it is supported by genes from different gene groups), the total number of annotation supported regions is not equal to the sum over the number of gene group-related annotation-supported promoter regions.