Table 4.

List of Tags Corresponding to Ribosomal Protein Genes with Statistically Significant Differences between Normal and Is65Dn Male Brain SAGE Library

Description TAG Normal males Trisomic males P Normal females 3T3 (Nor50K)
Ribosomal protein L26TGGGCATCCA41120.0000260
Ribosomal protein L5CTGCTATCCG3290.00031940
Ribosomal protein S8TGTAGTGTAA080.0035612
Ribosomal protein S6GCAGAGTGCG14320.00441985
Ribosomal protein S3CCCCAGCCAG48250.006542156
Ribosomal protein S19ACCAAGATCT1330.01121746
ESTS, highly similar to 60S RIBOSOMAL PROTEIN  L37 (Homo sapiens; Rattus norvegicus)GATTCCGTGA64390.011367108
Ribosomal protein S24GCCTTTATGA27120.01553043
Ribosomal protein S7TTCAGCTCGA19330.03033844
ESTs, weakly similar to Bacillus stearothermophilus  30S ribosomal protein S21 (Caenorhabditis elegans)TCCAACTCCT170.032772
EST, weakly similar to 60S ACIDIC RIBOSOMAL  PROTEIN P2 (Rattus norvegicus)GGATTTGGCT66450.03887844
Ribosomal protein s14TTGGCTGCCC28430.04224073
Ribosomal protein L30CCAGAACAGA26140.04642368
Ribosomal protein L37aAAAACAGTGF27150.04893536

[i] The identity for each tag (Description) and statistical significance (P) of observed differences between normal and Ts65Dn SAGE libraries are presented. The number of tags in SAGE libraries derived from normal (Normal males) or Ts65Dn (Trisomic males) mouse male brains, normal female brains (Normal females), and mouse embryonic cell line 3T3 are shown. Tags from the 3T3 SAGE library were normalized for a total of 50,000.