Table 3.

Some Disease-State/Tissue-Specific Gene Forms Isolated through CRAW Analysis

Some Library-Specific Forms with a Matching Gene in Public Databases
Fisher significance level Internal no. Library specificity Accession nos. of matching genes Common gene name; functional notes
0.00732615ovary tumor U66063, L07044 CAMK
0.011591ovary tumor D26156, D29175 transcriptional activator hSNF2b
0.01532240parathyroid tumor M60974 growth arrest and DNA damage-inducible protein
0.0224362cancer, various (cervical, colon) M88579, Z11773 zinc finger protein zfp-35 may act to control gene activity during prophase
0.0262335cancer, various (cervical, prostate) X87613 skeletal muscle-abundant protein
0.03325477cancer, various (cervical, colon, endometrial) M29204 binds to GC-rich sequences in epidermal growth factor
0.04017876cancer, various (colon, liver) X16396 NAD-dependent methylenetetrahydrofolate dehydrogenase
0.045717ovary tumor U18291 CDC-16, cell division control
0.04611462ovary tumor U49785, Y11151 dopachrome tautomerase (tyrosine-related protein 2), tumor antigen
0.05710942parathyroid tumor D83702 human brain mRNA for photolyase homolog, UV-induced DNA damage repair
0.11522783cancer, various (ovary, prostate) X79201 SYT, implicated in development of synovial sarcomas
0.21266ovary tumor X70218 protein phosphatase 4 (formerly X)
1.028992skin tumor I Z48804 ocular albinism gene

[i] Functional and library information for 78 UniGene 101 clusters, where subcluster membership was specific to libraries of a specific disease state or tissue. The first 41 entries highlight cancer libraries; the remaining 37 examples are from various libraries. For brevity, only the first 13 entries are shown. The full table may be viewed as supplementary information at htp://www.genome.org.