[i] A summary of our progress to date (September 1998) at each stage. Our effort covers 1100 Mb divided between the eight chromosomes listed. This total excludes the remaining 20 and 70 Mb on chromosomes 22 and X, respectively, that are currently being done by other maps. The first phase of the project is nearly complete, as the integrated landmark maps available for seven of the eight chromosomes exceeds a density of 15 markers/Mb. The markers are ordered as a single linkage group with a gap at the centromere of each chromosome. The few additional gaps in the YAC-based maps are closed using genetic or RH map information. In phase two of the project, markers from the landmark map have been used to isolate bacterial clones that have been assembled into contigs spanning ∼860 Mb. Contig lengths are approximate and have been estimated based on the number of fingerprint bands in the consensus map of each contig. The total given excludes any material on other chromosomes as much of this is done in collaborations with other groups. Phase three (walking and map closure) has been carried out only in limited regions of the genome so far. In the region of chromosome 22 currently in progress at the Sanger Centre, ∼20.2 Mb is currently contained in seven contigs, of which the largest is 14.7 Mb.