Synonymous and Nonsynonymous Substitution Rates
| Synonymous (× 109) | Nonsynonymous (× 109) | K a/K s | |
| CD4 | 2.93 ± 0.33 | 2.26 ± 0.15 | 0.77 |
| A-2 | 2.41 ± 0.22 | 0.14 ± 0.03 | 0.06 |
| B | 2.57 ± 0.25 | 0.41 ± 0.05 | 0.16 |
| GNB3 | 2.56 ± 0.32 | 0.11 ± 0.03 | 0.04 |
| C8 | 2.26 ± 0.32 | 1.03 ± 0.12 | 0.46 |
| ISOT-1 | 1.98 ± 0.16 | 0.06 ± 0.01 | 0.03 |
| TPI | 2.77 ± 0.40 | 0.16 ± 0.04 | 0.06 |
| C9 | 2.45 ± 0.34 | 0.32 ± 0.06 | 0.13 |
| ENO-2 | 2.01 ± 0.23 | 0.06 ± 0.02 | 0.03 |
| DRPLA | 2.33 ± 0.16 | 0.19 ± 0.02 | 0.08 |
| C10 | 3.07 ± 0.61 | 0.07 ± 0.04 | 0.02 |
| PTPN6 (hem) | 2.49 ± 0.24 | 0.18 ± 0.03 | 0.07 |
| BAP | 2.16 ± 0.29 | 0.01 ± 0.01 | 0.005 |
| C2f | 3.04 ± 0.44 | 0.43 ± 0.08 | 0.14 |
| C3f | 2.03 ± 0.25 | 0.35 ± 0.05 | 0.17 |
| B7 | 3.18 ± 0.40 | 0.88 ± 0.09 | 0.28 |
| Average | 2.52 ± 0.31 | 0.42 ± 0.05 | 0.16 |
[i] The numbers represent average substitution rate per nucleotide ± s.d., calculated by method 1 of Ina (1995). The estimate of human and rodent divergence of 80 million years was used in the calculation of rates (Li and Graur 1991). (K s) Substitution rate per synonymous site; (K a) substitution rate per nonsynonymous site.