[i] ^aAn amino acid sequence can be encoded by more than one nucleotide sequence. CDR3(nt) refers to the total number of observed nucleotide sequences that encode the number of amino acid sequences specified in the adjacent column.

[ii] *P < 0.0001, comparison of shared and unique using an unpaired, two-tailed t-test.

[iii] **P < 0.0001, comparison of shared and unique using one-way ANOVA, Newman-Keuls post hoc test.