Table 3.

Results of CRASA for Human Chromosomes 21 and 22 Compared With the Annotated Genes

Chr21 Chr22
No. of annotated genes (including pseudogenes)284 832 
 (1) No. of genes not available9 3 
 (2) No. of genes with 1 or 2 exons98 482 
 (3) No. of genes (exons) analyzed177 (1677)347 (3763)
  (3.1) No. of genes (exons) annotated by CRASA130 (1302)305 (3001)
  (3.2) No. of genes not annotated by CRASA47 42 
   (3.2.1) No. of putative or predicted genes4532 
   (3.2.2) No. of nonfunctional pseudogenes2 10 
No. of additional genes annotated by CRASA46 37 
 C1. Identical to known genes15 10 
  C.1.1. Total length13 8 
  C1.2. Partial length2 2 
 C2. Similar to known genes4 6 
  C2.1. Total length3 2 
  C2.2. Partial length1 4 
 C3. Not similar to any known genes16 11 
 C4. Pseudogenes4 0 
 C5. EST match only7 10 

[i] The genes that are not available means the mRNA sequences are not offered by the Consortium. The genes with 1 or 2 exons include 42 (or 341) functional genes and 56 (or 141) pseudogenes (processed or nonfunctional pseudogenes) on Chromosome 21 (or 22). The EST match only means the matched EST fragments are not open or the translated sequences <50 amino acids. The 1302 (or 3001) exons of Chromosome 21 (or 22) annotated by CRASA include 1145 (or 2556) exons both of whose boundaries are correctly matched and 157 (or 445) exons that are only partially matched to the actual exons.