Table 3.

Putative Genes Identified within the Mouse Syntenic Region of the SMCR

Group Gene names Accession number Exons mRNA (bp) ORF (aa) Expression profiles Reference[i] Human homologs
I. Genes 2010013E09Rik AK008226 51271111N/1.8, all; RT embryo (+) NT5M
Flj10193 AF467888 2740142N/4.0, 2.5, 1.3, all; RT/embryo (+) FLJ10193
Rasd1 NM_00902621623280N/2.1, heart, brain, kidney, and liver Kemppainen and Behrend 1998 RASD1
Pemt NM_0088197600200N/1.0, only liver after birth Walkey et al. 1996 PEMT
Rai1 NM_009021272221840RT/adult (+), before embryo 10 dpc (+) RAII
Srebf1 AF374266 1835701076RT/ubiquitous SREBF1
Tom112 AF467887 151678507N/all, with 7 splice variants; RT/embryo (+) TOM1L2
4930449E07Rik AK015430 141860523N/2.2, predominantly in testis; RT/embryo at 15 dpc (+) DKFZp586M1120
Atp12 BC013607 81813289RT/ubiquitous ATP12
4933439F18Rik AK017120 81717217N/2.0, all except spleen; RT/embryo (+) MGC3048
Drg2 NM_021354131713364N/2.0, low in sk. mus. Li et al. 2000 DRG2
Myo15 NM_01086266117693511N/1.2, pituitary gland Liang et al. 1999 MYO15A
LIglh NM_0085022242791034RT/adult (+), embryo (+) Tomotsune et al. 1993 LLGLI
Fliih NM_0220093140121271RT/adult (+), embryo (+) FLII
Top3a AB006074 2037411003N/3.8, predominantly in testis Seki et al. 1998 TOP3A
Shmtl AF237702 131771478N/2.1, 3.2, liver Liu et al. 2001 SHMT1
II. Predicted genes 1700013G23Rik AK005951 2293NART/testis
Flj20308 BI412421 3783NAN/6.0, 3.5; ubiquitous FLJ20308
Ubl NA2clusterNART/ubiquitous
Pabplp NA2clusterNART/testis, weak in embryos 10 dpc and 15 dpc
Smcr7 BF582554 1694NAN/2.6, heart, liver; RT/embryo after 10 dpc (+) SMCR7
Smcr8 AK010198 11050NAN/7.5, 3.8-all except sk. mus.; RT/embryo (+) SMCR8
III. Pseudogene Rps4
Protein tyrosine phosphatase 1F2
Gapd

[i] References for gene expression profile. NA, not available. For the gene expression profile, N means data from Northern blotting, and the numbers after the N are the sizes of transcripts in kilobases; RT means data from RT-PCR analyses. Reference is for gene expression profile.