Table 3.

Summary of Suggestive Changes in Gene Expression Identified in Comparisons between the Strain Groups Shown in Table 2

Comparison No. of changes (unique) No. of potential 1° changes No. of control changes
locus tissue up down
Idd3 S1 (1)2 (2)02
T4 (3)1 (1)01
Idd5 S38 (37)1 (1)01
T7 (7)6 (6)01
Idd3+5 S30 (28)1 (1)22
T48 (48)2 (2)42
Idd9 S9 (9)9 (6)7[ii] 1
T7 (7)4 (4)[iii] 4[iii] 2[iii]
Idd3, Idd5, Idd3+5, Idd9 S0 (0)2 (2)0
T2 (2)3 (3)1
otherS141 (121)153 (131)0
total287 (263)186 (159)1713

[i] Full details of all changes are given in the supplementary material.

[ii] Only five genes were unique.

[iii] Includes only genes that met the original criteria for a suggestive change. An additional six probe sets met the modified criteria for a suggestive decrease in expression, including two potential primary changes. A further five control probe sets also passed the modified criteria (see supplemental Fig. 1 [http: //www.gen.cimr.cam.ac.uk/todd/]).