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Table 3.

Observed and Expected Numbers of Symmetrical Class 1 Domains and Domain Families in Humans[i]

	Comb.[ii]	Obs.[iii]	Exp.[iv]	P
Domains (345)	0–0	29	5.3	<10⁻¹⁰
	1–1	257	226.2	<10⁻³
	2–2	2	1.4	n.d.
	$\sum$	288	233	<10⁻⁷
Domain family (56)	0–0	8.5	5.2	0.13
	1–1	24.3	17.9	0.07
	2–2	0.2	0.8	n.d.
	$\sum$	33	23.8	<0.05

[i] The total number of class 1 domains and families are indicated in parentheses. Summed symmetrical combinations are shown in boldface. The expected values were calculated based on the frequencies of flanking intron phases. Some P-values were not determined (n.d.) due to the low sample size.

[ii] combination of flanking intron phases.

[iii] Observed.

[iv] Expected.