Table 3.

Summary of Northern Blot Expression Profiles of Putative Genes in the CESCR, Listed in Order of Location from the Centromere

Gene name Probe used Size of transcript(s) in kb Tissues showing expression[ii]
CECR8 cDNA 18400411.4Testis
IL-17R 697 bp PCR fragment (primers IL17-F1  and R1), 3′ end of coding region1.05, 1.45, 1.9, 2.6, 5.0,  6.3, 8.8, and 10.5All
cDNA 310354, most proximal EST cluster1.05 and 6.3All
cDNA 366663, most distal EST cluster1.05, 2.6 and 8.8All
CECR6 cDNA 464145All, especially adult heart, brain, prostate,  testes, peripheral blood leukocytes, and  fetal brain (not all shown in Fig. 5)
CECR5 Single-stranded antisense of cDNA  19536251.9All
CECR4 cDNA 3216867Adult heart and skeletal muscle, all fetal  tissues tested
CECR3 cDNA2.4 and 3.72.4 kb—predominantly in lung;  3.7 kg—weakly in all tissues
CECR9 Amplified exon2All, especially heart
SLC25A18 cDNA 289492.3, 2.2, and 3.62.3 kb—adult and fetal brain;  2.2 kb—adult and fetal liver;  3.6 kb—adult liver
ATP6E cDNA 61EW1.5All
MIL1 cDNA 15418221.3, 2.4, 4.0, 5.0 and 10All

[i] The expression pattern of CECR1 was reported previously (Riazi et al. 2000). CECR7 was not analyzed, due to the sequence similarlity to multiple other genes. The pattern ofCECR2 expression will be reported elsewhere.

[ii] Tissues tested: heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas. Some genes were also tested for uterus, colon, small intestine, bladder, stomach, spleen, thyroid, prostate, testis, ovary, peripheral blood leukocytes, fetal brain, fetal lung, fetal liver, fetal kidney, and fetal muscle.