Partitioning into Clades
| Clade identifier | Name | Members[i] | RPC[ii] | %[iii] |
| a | antitrypsin-like | AAT ∣ xlaAP ∣ ACH ∣ PCI ∣ TBG ∣ CBG ∣ KAL ∣ Carp serpins ∣ EP45 ∣ UTMP ∣ RASP-1 ∣ ANGT | Y | 100 |
| b | intracellular | SCCA-1/2 ∣ PI-6 and SPI-3 ∣ PI-8 and SPI-6 ∣ PI-9 ∣ ovalbumin ∣ PAI-2 ∣ maspin ∣ MNEI ∣ MENT ∣ bomapin ∣ megsin | P (9/11) | 100 |
| c | antithrombin | ANT | s | |
| d | heparin cofactor II | HEPII | s | |
| e | PAI-1/GDN | PAI-1 ∣ GDN ∣mviSERP-1 | Y | 97.4 |
| f | PEDF | PEDF ∣ A2AP ∣pma | N | 92.3 |
| g | C1-inhibitor | C1-I | s | |
| h | heat shock protein 47 | HSP47 | s | |
| i | neuroserpin | NEUS ∣ TSA | N | 95.1 |
| j | horseshoe crab | LICI-1/2/3 | s | |
| k | insects | mseSERP-1 ∣ BmoACH-II and AAT ∣ mseSERP-2 | P (2/3) | 94.4 |
| l | nematodes | Caenorhabditis elegans (7 clades) | P (6/7) | 100 |
| m | blood fluke | Schistosoma mansoni, japonicum, andhaematobium | s | |
| n | viral Serpin-1/2 | SPI-1/2 | s | |
| o | viral Serpin-3 | SPI-3 | s | |
| p | plants | barley, wheat, oat, and thale cress | s |
[i] The symbol (∣) separates groups of sequences identified in 100% of bootstrap trees using the strict consensus method (Sokal and Rohlf 1981).
[ii] Recognized as members of a reduced partition consensus (RPC) clade using STRICT (REDCON 2.0; Wilkinson 1996). (Y) yes; (N) no; (P) partial. The RPC contains fewer members but otherwise agrees; the level of agreement is shown as a fraction.
[iii] The analysis was performed using the comparison method. Percentage scores >90% are significant (see Fig. 8A). (s) Those clades identified solely by the strict consensus method. These are subgroups with 100% bootstrap values in the distance tree, which were not found to associate with any other sequences.