Table 2.

Transcripts Located between D16S468/D16S3070 and Cosmid 377A12

Clone size[i] Accession no.Expression Data[ii] Database homology[iii] Methods of identification[v] RACE[vii]
size(s) on Northern blot (kb)tissue specif.
BLASTN ( P) BLASTX ( P) dbEST[iv] DS[vi] ET[vi] [vii] SS[vi] CS[vi] [vii]
R44239 (1.8) R44239 5.0allnonenone4+N.A.N.D.
Gene 1 (1.1) AA631968 6, 6.8K, Th, Spnonenone1+1+N.A.N.D.
NK4 (1.0) M59807 1.0allnonenone20++N.A.N.D.
ZNF210 (2.2) AF060865 5, 3H, Sm, PKIAA03226 (10−114)MLZ-4 (10−89)126+N.A.5′
PL59 (1.4) AF098968 mult (<2.5)allnonenone2+3+N.A.5′, 3′
ZNF213 (3.2) AF017433 3.8all FPM (10−44) ZNF20 (10−56)0+2+N.A.N.D.
V9 (1.4) AF098666 1.4Sp, Sinone Caspase-6 (10−7)02++5′
v57c10 (0.5) AF098665 N.F.brain (cDNA)[viii] nonenone0++5′
v57c7 (0.7) AF098667 N.F.brain (cDNA)[viii] nonenone11++5′, 3′
OR1F1 (0.9)[ix] Y14442 N.D.N.A.RATOLFPROC (10−245)OLF5_RAT (10−161)0++N.D.
OR1F2 (0.9)[ix] AJ003145 N.D.N.A.RATOLFPROC (10−178)OLF5_RAT (10−152)0++N.D.
ZNF200 (2.1) AF060866 2–4all ZNF184 (10−45)ZNFZ135_HU (10−50)5+1++N.D.
MEFV (3.5) AF018080 3.7neutrophils HUMRFPA (10−51)HUMRFPA (10−107)02+N.A.N.D.
FPM315 (3.5) AA631982 3.5, 4.0all ZNF20 (10−126)ZNF20 (10−137)7++N.A.N.D.
Clone 7 (0.4) AA631981 3.6all ZNF75 (10−35)ZNF75 (10−12)0++N.A.N.D.
OR2C1 (0.9)[ix] [x] AF098664 N.D.N.A. MUSOR3X (10−247)MUSOR3 (10−176)0N.D.+N.A.N.D.

[i] Size of largest cDNA clone or composite of several overlapping clones (in kb).

[ii] Tissues are designated as follows: (H) Heart; (K) kidney; (P) pancreas; (Si) small intestine; (Sp) spleen; (Th) thymus; (Sm) smooth muscle. (Mult) Multiple bands observed.

[iii] For BLASTN and BLASTX analysis the gene with lowestP value (<0.05) is shown in parentheses.

[iv] The number of EST clones with nearly identical DNA sequence to a given FMF region gene are indicated.

[v] (DS) Direct selection, (ET) exon trapping; (SS) sample sequencing; (CS) complete sequencing. (+) Clone identified, (−) no clone found; number of independent exon trap clones identified shown.

[vi] Sequences of cDNAs identified by other methods present in whole or in part indicated by +.

[vii] (N.A.) Not applicable; (N.D.) not done.

[viii] Screened by RT–PCR.

[ix] Size of putative ORF based on sequence homology.

[x] This transcript lies outside the 285-kb interval subjected to multiple methods of transcript identification.