Table 2.

Insertions and Deletions in PrP Gene Intron 2

Locus Length (bp) Percent repeats Events since mammalian radiation (kb) original length (kb)
inserts deletions net gain
Human9,970602.51.70.99.1
Mouse18,0126910.21.38.99.1
Sheep14,031717.42.54.99.1

[i] Insertions and deletions in intron 2 of the PrPgenes. For each species the total number of bases in intron 2 occupied by species-specific interspersed repeats was calculated. The size of the deletions was calculated from the size of the orthologous regions in the other species, disregarding species-specific repeats in those regions. In all three species one comes to an estimate for the length of this intron before the mammalian radiation of 9.1 kb.