Table 2.

Relationships Between Divisions and Homology Search Files

Database division BLAST databases at NCBI FASTA databases at EBI Location of “finished” HTG records
BCTnr,[ii] monthemall, emnew, ebact
PROemall, emnew, epro
FUNemall, emnew, efun
HUMemall, emnew, ehum H. sapiens(EMBL)
PRInr, month H. sapiens(GenBank)
RODnr, monthemall, emnew, erod
MAMnr, monthemall, emnew, emam
VRTnr, monthemall, emnew, evrt
INVnr, monthemall, emnew, einv C. elegans and  D. melanogaster
PLNnr,[iii] monthemall, emnew, epln A. thaliana
ORGemall, emnew, eorg
VRLnr, monthemall, emnew, evrl
PHGnr, monthemall, emnew, ephg
RNAnr, monthemall, emnew, erna
SYNnr, monthemall, emnew, esyn
UNAnr, monthemall, emnew, euna
ESTdbest,[iv]montheest
STSdbsts, monthests
GSSdbgss, monthemall, emnew
HTGhtgs, monthemall, emnewIncludes all “unfinished”  HTG
PATnr, monthemall, emnew, epat

[i] (month) A rolling month database consisting of nucleotide or protein sequences added to nr in the last 28 days; (nr) a nonredundant nucleotide (or protein) database of all sequences, excluding ESTs, STSs, GSSs, and HTGs; (emnew) new EMBL entries since latest release; (emall) all EMBL entries, latest release + new (other FASTA database acronyms are derived from the EMBL division to which they correspond).

[ii] NCBI offers ecoli as a separate BLAST database for queries against Escherichia coli genome and protein sequences.

[iii] NCBI offers yeast as a separate BLAST database for queries against the Saccharomyces cerevisiae genome and protein sequences.

[iv] NCBI plans to split dbest into three files of human only, mouse only, and all nonhuman, nonmouse ESTs.