Table 2.

Summary of First 1063 Mutations Discovered and Sequenced by ATP

Fragment identifier ∼1 kb Total Truncations Missense Silent
atapp110244
atapm17133
athsp710046
lmwptp4013
versuc7223
cpl17016
atapl17151
fagpt29063
cip88161
parpc110154
nph39063
troubl12075
chubby8143
tubby11155
athsp8134
arp7025
lec15041
abf3-110163
1755122
abp111173
c7a1077052
at_wrn9135
recq126042
pif216079
cyk8140104
For the first 110 orders
Average9.6
Range4–33
Total106348528487
Percent4.549.745.8

[i] For purposes of illustration, only the first 25 completed screens are individually represented. The average, range, totals, and percentages in the table are for all 110 loci screened during the first year of public operation. For each gene fragment, the total number of mutations sequenced is listed. Mutations are divided into three categories; truncations represent changes causing a premature stop codon or changes altering the canonical intron donor/acceptor splice sites. Missense changes are any nucleotide changes in coding regions that change the amino acid coded. Silent changes represent mutations falling outside the coding region, within an intron, or changes in codons not altering the encoded amino acid. Users have the option to request additional screens should more mutations be desired.