Table 2.

Comparison of Genome Coverage

chr20 CDS 3′UTR 5′UTR upstream
Blastz all40.5%98.5%87.1%89.0%87.2%
Blastz tight5.6%92.5%26.0%39.6%28.3%
PH all29.7%95.5%55.0%59.3%52.5%
PH tight5.0%91.2%25.1%36.3%25.2%
transl. BLAT5.8%90.3%29.2%38.4%27.2%

[i] Percentage of human chromosome 20, and various gene features on this chromosome covered by BLASTZ, PatternHunter, and translated BLAT in alignments between this chromosome and the mouse genome. The CDS, 3′ UTR, 5′ UTR, and upstream columns are based on RefSeq (Pruit and Maglott 2001) mRNA defined genes available at the Human Genome Browswer (http://genome.ucsc.edu; Kent et al. 2002). The upstream column is 200 bases upstream of transcription start for genes in which there is an annotated 5′ UTR. For the BLASTZ and PatternHunter alignments, subsets relatively specific to coding regions were constructed by rescoring the alignments using the substitution scores

ACGTA100200100200C200100200100G100200100200T200100200100

[ii] a gap open score of −2000, a gap extension score of −50, and a threshold of 3400.