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Table 2.

Likelihood Ratio Test Results

Group	n [i]	P-value[ii] M0:M1	P-value M7:M8	M8 Estimates[iii]	Positively Selected Positions[iv]
1	11	6.0e-6	1.6e-04	ω = 0.75;P ₁ = 0.00
2	6	<1.0e-6	<1.0e-6	ω = 3.69;P ₁ = 0.08	263 C 489 W 573 S 599 S 621 F 667 G 693 I 730 R 754 F 756 Q 774 H 779 N 796 V 797 S 839 S 842 M 938 T 939 E 940 S 942 Y 945 V
3	2	0.009
4	2	<1.0e-6
5	10	0.002	<1.0e-6	ω = 0.23;P ₁ = 0.55
6	2	0.023
7	9	3.1e-5	1.0	ω = 0.50;P ₁ = 0.0
8	4	0.040	8.5e-5	ω = 1.81;P ₁ = 0.20	97 Q 714 V 730 L 759 E
9	4	<1.0e-6	<1.0e-6	ω = 3.73;P ₁ = 0.12	111 R 305 H 372 H 474 R 562 Q 703 E 795 H
10	6	0.094	<1.0e-6	ω = 3.80;P ₁ = 0.04	553 K 577 S 722 G 784 F 843 E
11	4	0.006	<1.0e-6	ω = 8.89;P ₁ = 0.10	7 L 10 S 388 Q 427 K 431 Y 481 Y 534 D 604 N 626 T 629 D 676 V 717 S 719 R 738 E 758 E 779 V 781 L 817 N 840 S 841 N862 E
12	3	0.002	<1.0e-6	ω = 7.18;P ₁ = 0.06	2 L 423 P 594 L 782 C 815 D 819 R 859 E 862 P
13	2	0.008
14	10	0.004	<1.0e-6	ω = 3.80;P ₁ = 0.07	108 V 581 W 590 K 609 K 634 L 636 R 659 T 662 S 679 R 682 F 683 N 724 T 726 G 753 R 754 T 755 P 756 D 780 N 802 S 804 D 805 G 826 R 828 D 829 F 830 R 853 W
15	3	0.641	6.0e-6	ω = 4.04;P ₁ = 0.08	581 W 640 E 699 M 729 P 759 S 797 L 798 S 852 S 853 K
16	4	0.024	0.258	ω = 1.16;P ₁ = 0.14
17	2	0.001
18	5	0.076	6.1e-5	ω = 2.28;P ₁ = 0.07	805 L
19	2	0.003
20	8	0.002	<1.0e-6	ω = 3.43;P ₁ = 0.08	602 E 649 W 650 Y 662 L 672 S 950 Y 967 E 1126 G 1195 F 1218 T 1224 S 1225 C 1227 P 1229 S
21	2	7.1e-4
22	2	2.0e-6

[i] Number of sequences in the group.

[ii] P-values in bold represent significant tests in which ω is inferred to be >1.0. P-values are Bonferroni corrected for the number of tests within a column and an experimental Type I error of 0.05.

[iii] ω is d _N:d _Sestimated under M8; P ₁ is the inferred proportion of positively selected sites.

[iv] Position locations are based on alignments with gaps. Underlined positions are those common to the results of the analyses of the complete and domain alignments.