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Table 2.

Extreme Pathway Characteristics Associated with the Production of the Indicated Amino Acids

Amino Acid		Case 1		Case 2		Case 3		Case 4
Amino Acid		no. of EP	no. of ES	no. of EP/ES	no. of EP	no. of ES	no. of EP/ES	no. of EP	no. of ES	no. of EP/ES	no. of EP	no. of ES	no. of EP/ES
Asparigine	217	105	2.1	295	154	1.9	295	154	1.9	340	193	1.8
Aspartic Acid	360	102	3.5	466	142	3.3	466	142	3.3	491	163	3.0
Cysteine	473	232	2.0	822	420	2.0	822	420	2.0	1022	612	1.7
Glutamine	249	101	2.5	290	140	2.1	290	140	2.1	315	164	1.9
Glutamic Acid	441	148	3.0	473	178	2.7	473	178	2.7	493	198	2.5
Glycine	0	···	···	0	···	···	348	149	2.3	377	173	2.2
Lysine	474	167	2.8	587	213	2.8	587	213	2.8	611	237	2.6
Proline	479	149	3.2	621	209	3.0	621	209	3.0	867	326	2.7
Serine	212	101	2.1	326	158	2.1	326	158	2.1	355	186	1.9
Threonine	275	136	2.0	432	206	2.1	432	206	2.1	469	242	1.9
Tryptophan	936	615	1.5	1431	1034	1.4	1431	1034	1.4	1958	1486	1.3
Tyrosine	584	302	1.9	825	477	1.7	825	477	1.7	1008	649	1.6
Average	392	196	2.4	547	303	2.3	576	290	2.3	692	386	2.1

[i] The various cases refer to changes in the carbon sinks of the network (see Fig. 2). Case 1: succinate; Case 2: succinate, acetate; Case 3: succinate, acetate, formate; Case 4: succinate, acetate, formate, lactate. EP indicates extreme pathway in above table; and ES, unique external state.