Putative Genes Identified within the SMCR
| Group | Gene name | Accession number | Exons | mRNA (bp) | ORF (aa) | Domains | Expression profiles | Reference[i] |
| I. Genes | NT5M | NM_020201 | 5 | 1617 | 228 | NA | N/1.4, heart, brain, and muscle | Rampazzo et al. 2000 |
| RPL13 | NM_000977 | 1 | 1110 | 211 | NA | RT/ubiquitous | ||
| FLJ10193 | NM_018019 | 2 | 2222 | 146 | NA | N/2.4, ubiquitous | ||
| RASD1 | NM_016084 | 2 | 1740 | 281 | RAS, etc. | N/5.0, all, predominantly in heart | Tu et al. 1999 | |
| PEMT | NM_007169 | 9 | 1007 | 199 | NA | N/1.0, liver | Shields et al. 2001 | |
| RA11 | NM_030665 | 7 | 5667 | 1862 | NA | N/8.0, all, 1.5-placenta, 10.0-weak | Seranski et al. 2001 | |
| SREBF1 | NM_004176 | 22 | 4154 | 1147 | HLH | N/4.0, all, predominantly in liver, adrenal gland | Yokoyama et al. 1993 | |
| TOM1L2 | AF467441 | 16 | 1903 | 475 | VHS, GAT | N/6.0, 2.4, all, predominantly in heart, sk. mus.; RT/fetus (+) | ||
| DKFZp586M1120 | AL136926 | 11 | 5822 | 225 | LRR | N/1.8, predominantly in kidney; RT/fetus (+) | ||
| ATP12 | AF052185 | 8 | 1320 | 289 | NA | N/1.4, all, weak in brain, placenta, lung; RT/fetus (+) | ||
| MGC3048 | NM_024052 | 6 | 816 | 217 | NA | N/4.4, ubiquitous | ||
| DRG2 | NM_001388 | 13 | 1880 | 365 | GTP-OBG, etc. | N/1.4, 2.0, all, high level in sk. mus., heart, and kidney | Li et al. 2000 | |
| MYO15A | NM_016239 | 66 | 11876 | 3530 | MyTH4, etc. | N/12.0, pituitary gland | Liang et al. 1999 | |
| FLJ20308 | AK000315 | 4 | 2371 | 378 | NA | N/3.5, 4.0, ubiquitous; RT/fetus (+) | ||
| LLGL1 | D50550 | 22 | 3806 | 1032 | NA | N/4.4, all, more abundantly in brain and testis | Koyama et al. 1996 | |
| FL11 | NM_002018 | 30 | 14131 | 1269 | GEL, LRR | N/4.4, predominantly in sk. mus. | Campbell et al. 1997 | |
| SMCR7 | AF467443 | 4 | 2455 | 454 | NA | N/2.4, 3.4, all, predominantly in heart, sk. mus., RT/fetus (+) | ||
| TOP3A | U43431 | 19 | 3755 | 1001 | TOP | N/7.2, 6, 4, ubiquitous | Fritz et al. 1997 | |
| SMCR8 | AF467440 | 2 | 3206 | 787 | LBP/BPI/CETP | N/2.8, 3.0, 6.5, all; RT/fetus (+) | ||
| SHMT1 | XM_039898 | 13 | 1867 | 483 | SHMT | N/2.3, 2.1, predominantly in liver, kidney | Girgis et al. 1998 | |
| II. Predicted genes | SMCR9 | NA | 3 | 543 | 180 | PDZ | RT/adult (+), fetus (+) | |
| FLJ23022 | NM_025051 | 1 | 2145 | 147 | NA | RT/adult (+), fetus (+) | ||
| SMCR2 | AI821758 | 4 | 2255 | NA | NA | RT/adult brain, leukemia, fetus (+) | ||
| SMCR3 | AA609047 | 1 | 3235 | NA | NA | RT/adult (+), fetus (+) | ||
| SMCR4 | BG992883 | 3 | 502 | NA | NA | RT/adult (+), fetus (+) | ||
| SMCR5 | AF467442 | 1 | 2843 | 140 | NA | RT/ubiquitous | ||
| SMCR6 | BF511382 | 3 | 588 | NA | NA | RT/ubiquitous | ||
| DKFZp586E1520 | AL133641 | 1 | 1328 | 136 | NA | RT/ubiquitous | ||
| FLJ21501 | AK025154 | 1 | 3203 | NA | NA | RT/ubiquitous | ||
| FLJ13773 | AK023835 | 1 | 4512 | NA | NA | RT/adult (+), fetus (+) | ||
| III. Pseudogenes | EVPL | |||||||
| RPL7A | ||||||||
| RPL21 |
[i] References for gene expression profile. Alternative splicing was observed for genes PEMT, RAII, SREBF1, ATP12, SMCR7, DRG2, and SHMT1. The gene description for them is about the major transcripts. NA, not available. For the gene expression profile, N means data from Northern blotting, and the numbers after the N are the sizes of transcripts in kilobases; RT means data from RT-PCR analyses.