Table 2.

Searching Promoters for Genes with Known Complete Coding Region

Programs Training set of 133 promoters Test set of 120 promoters
true prediction (sensitivity) false prediction (FP/AllP) undetected true prediction (sensitivity) false prediction (FP/AllP) undetected
PROSCAN1.7 31 (23%)21 (40%)8126 (22%)28 (52%)66
NNPP2.0 63 (47%)50 (44%)2124 (20%)63 (72%)33
PromFD1.0 53 (40%)44 (45%)4860 (50%)63 (51%)10
promoter2.0 9 (7%)101 (92%)2310 (8%)92 (90%)18
TSSG 78 (57%)13 (14%)4256 (47%)27 (33%)37
TSSW 58 (44%)36 (38%)3956 (47%)38 (40%)26
CONPRO 86 (65%)9 (9%)3875 (63%)10 (12%)35

[i] The CONPRO can detect promoters for about half of the human genes with mRNA known. For the promoters predicted, about 88% of them are true promoters. Additional information is given in the legend of Table 1.