Table 2.

Strain Groupings Used to Identify Differentially Expressed Genes

Iddlocus/loci influencing expression level Treatment group Control group
Idd3 Idd3, Idd3+5 NOD, Idd5, Idd9
Idd5 Idd5, Idd3+5 NOD, Idd3, Idd9
Idd3+5 Idd3+5 NOD, Idd3, Idd5, Idd9
Idd9 Idd9 NOD, Idd3, Idd5, Idd3+5
Idd3, Idd5, Idd3+5, and Idd9 Idd3, Idd5, Idd3+5, Idd9 NOD
otherB10NOD, Idd3, Idd5, Idd3+5, Idd9

[i] For each comparison, the treatment group was defined as comprising those NOD-derived congenic strains carrying the C57BL/6, or B10 resistance allele at the locus of interest. Conversely, the control group consisted of those NOD-derived strains carrying the NOD susceptibility allele at the locus in question.