Table 2.

Minimum Numbers of Genetic Events (Character Changes) Required to Explain the Occurrence of Gene Family Members on Human Chromosomes 2, 7, 12, and 17

Gene family Tandem Genome
Dup Tra Total Dup Tra Del/Tra Total
ACT 2241146
ACAD 3253249
ARF 3253249
AE 2240011
CDK 43733410
ERBB 5383349
GLI 2240011
GNB 1121146
GPR 851342410
IF 25328242430
IGBP 5381023
INHB 3251146
INTA 64103137
INTB 4373249
NHR 731054413
NOS 2240011
PSMB 1121146
RASR 741174415
SCN 2131135
WNT  + Genome  Duplication3253249
Total145167

[i] Minimum numbers of genetic events (character changes) required to explain the occurrence of gene family members on human chromosomes 2, 7, 12, and 17, given the phylogenies obtained (see Fig. 1) under the tandem duplication and whole genome duplication models. Genetic events: Dup, tandem duplication; Tra, translocation; Del/Tra, deletion or translocation to another chromosome (i.e., not 2, 7, 12, or 17). Abbreviations of gene family names are as given in Table 1.