Table 2.

Characterization of EDC Genes Encoding Known Proteins

YAC probe Detected transcript (gene) Size of cDNA Homologous to: acc. no. (identities) Positive YACs
Established EDC genes
Involucrin2139 bp M13902 /M13903 874_d_5, 986_e_10, 890_e_4,
(IVL)(99%) 955_e_11
Small proline-rich protein 3890 bp / 859 bp AF077374 874_d_5, 986_e_10, 890_e_4,
(SPRR3)(99% / 95%) 955_e_11, 692_c_1
986_e_10Small proline-rich protein 1A/1B769 bp / 595 bp L05187 (99%) /874_d_5, 986_e_10, 890_e_4,
(SPRR1A/1B)M84757(99%) 955_e_11, 692_c_1
Small proline-rich protein 2A/2B674 bp / 661 bp M20030 (99%) /874_d_5, 986_e_10, 890_e_4,
(SPRR2A/2B)M21302(99%) 955_e_11, 692_c_1
S100 Calcium-binding protein A7416 bp M86757 955_e_11, 692_c_1, 100_f_3,
(S100A7)(99%) 950_e_2 (#1, #2, #4–#11)
S100 Calcium-binding protein A6420 bp M14300 955_e_11, 692_c_1, 100_f_3,
(S100A6)(100%) 950_e_2 (#4, #6, #7, #9, #11)
S100 Calcium-binding protein A4496 bp M80563 955_e_11, 692_c_1, 100_f_3,
(S100A4)(99%) 950_e_2 (#4, #6, #7, #9, #11)
New-assigned EDC genes
Adenosine deaminase, RNA-specific2625 bp[i] U18121 950_e_2 (#1–#11),
950_e_2#9(ADAR1)(99%) 951_f_6, 954_a_11
Cytoskeletal tropomyosin TM30nm2075 bp X04588 950_e_2 (#2, #4, #7, #9),
(TPM3)(99%)713_h_12, 951_f_6
26S Proteasome subunit p31973 bp D38047 950_e_2 (#2–#4, #7–#10),
(PSMD8L)(100%) 951_f_6, 954_a_11
HAX-1, HS1-binding protein1084 bp U68566 950_e_2 (#2–#4, #7, #9),
(HAX1)(99%)713_h_12, 951_f_6, 643_h_5
34 / 67 kd Laminin receptor1025 bp J03799 950_e_2 (#2–#4, #7–#10),
(LAMRL6)(99%) 951_f_6, 643_h_5, 954_a_11

[i] All sequenced cDNA inserts originated from the 3′ untranslated region (UTR) of the gene.