Table 2.

Numbers of Genes n diff Showing Different Tumor/Normal Ratios between Clinicopathological Subgroups

Subgroups n diff
Clear cell (32)stage I-III (22) vs. IV,M (10)43
stage I-IV (27) vs. M (5)28
stage I (9) vs. II-IV,M (23)9
grade 1 (7) vs. 2,3 (25)16
Clear cell (32) vs. chromophobe (4)123

[i] The genes were identified by permutation t-tests at single-test significance levels of α = 10−3 out of ∼20,000 cDNAs that had no consistently low intensity, leading to an expected number of ≤20 false positives. The “Chromophobe vs. clear cell” distinction shows the most pronounced molecular differences.