Table 2.

Divergence in Restriction/Modification Systems in Campylobacter jejuni Strains

Gene Function[iii] Clone content (%) Phase variable[iv] 81116 81-176 X G1 P1 P2 P3 P4 PHLS 01 PHLS 02 PHLS 03
Cj0031 type IIS restriction/ modification enzyme, N-terminal half Cj0031 (31)√+++++++++++
Cj0032 type IIS restriction/ modification enzyme, C-terminal half Cj0031 (8) Cj0032 (95)√−+−+−+(+)−++(+)
Cj0208 DNA modification methylase Cj0207 (1) Cj0208(66)+++++++++++
Cj0690 possible restriction/ modification enzyme Cj0690 (34)−++++(+)+++++
Cj0722 DNA methylase Cj0721 (16) Cj0722 (100) Cj0723 (32)+++++(+)++(+)++
Cj1051 restriction/modification enzyme Cj1051 (25)+−+++−−+++(+)
Cj1549 type I restriction enzyme R protein Cj1549(27)−++++++−+++
Cj1551 type I restriction enzyme S protein Cj1551 (56)−++++++−+++
Cj1553 type I restriction enzyme M protein Cj1553 (39)+++++++−+++

[i] A + or − indicates that the red/green hybridization signal intensity ratio is >0.5 or <0.5. respectively.

[ii] (+) Indicates the possibility that the gene may be absent or highly divergent even though the red/green hybridization signal intensity ratio is > 0.5 (see Methods).

[iii] Putative gene function based on annotation (Parkhill et al. 2000).

[iv] Genes contain intragenic homopolymeric tracts indicating potential phase variable expression (Parkhill et al. 2000).