Analysis of Chromosome 21 Genes for Overlap with Conserved Elements
| Class[i] | Analyzed[ii] | Conserved[iii] | |
| Known genes | 1.1 | 94 | 88 |
| 1.2 | 17 | 15 | |
| Related genes | 2.1 | 9 | 8 |
| 2.2 | 0 | ||
| Protein motifs | 3.1 | 8 | 7 |
| 3.2 | 1 | 0 | |
| Predicted | 4.1 | 12 | 6 |
| 4.2 | 16 | 2 | |
| 4.3 | 27 | 4 |
[i] Class definitions according to Hattori et al. (2000). Briefly: (1.1) genes with 100% identity and known function; (1.2) genes with 100% identity but unknown function; (2.1) genes with similarity to known genes with assigned function; (2.2) genes with similarity to known genes without assigned function; (3.1) genes with similarity to a characterized functional motif; (3.2) genes with similarity to defined region of a known protein without functional association; (4.1) genes predicted based on spliced EST matches and ab initio predicted exons; (4.2) genes predicted on splice EST matches; (4.3) genes predicted on ab initio predicted exons.
[ii] The number of genes analyzed by cross-species comparison.
[iii] The number of genes with at least one exon conserved.