Table 2.

Average Nonsynonymous (Ka) and Synonymous (Ks) Substitution Rate in Orthologous Genes Between Human and Murids According to their Number of Pseudogenes

No. of retropseudogenes Ka Ks Ks_nd
0 (n = 349)0.109 ± 0.0950.519 ± 0.1490.396 ± 0.103
1 (n = 96)0.044 ± 0.0630.470 ± 0.2410.421 ± 0.236
2 (n = 22)0.022 ± 0.0420.470 ± 0.1340.436 ± 0.099
≥3 (n = 13)0.026 ± 0.0450.437 ± 0.1350.399 ± 0.13

[i] Rate according to no. of pseudogenes = mean value ±s.d. Ks_nd:Ks computed after removing doublet substitutions (see Duret and Mouchiroud 2000). The number of genes is indicated for each sample.