Mean Nucleotide Diversity of Multiple Haplotype Comparisons within the Class I Region of the MHC (β Block)
| Regions[i] | ||||||||||||||||||
| i | ii | iii | iv | v | ||||||||||||||
| AHs[ii] | 44.1 | 57.1 | 8.1 | AHs | 44.1 | 57.1 | 62.1 | AHs | 44.1 | 62.1 | AHs | 44.1 | 57.1 | AHs | 44.1 | 57.1 | 8.1 | |
| Mean nucleotide diversity (%) | 44.1 | 44.1 | 44.1 | 44.1 | 44.1 | |||||||||||||
| 57.1 | 0.18 | 57.1 | 0.13 | 57.1 | 0.58 | 57.1 | 1.64 | |||||||||||
| 8.1 | 0.13 | 0.26 | 8.1 | 1.07 | 1.67 | |||||||||||||
| 62.1 | 0.08 | 0.23 | 0.15 | 62.1 | 1.07 | 1.14 | 62.1 | 0.29 | 62.1 | 0.31 | 0.43 | |||||||
| 18.2 | 0.73 | 0.8 | 1.37 | 7.1 | 0.46 | 0.49 | 7.1 | 1.07 | 1.74 | 0.25 | ||||||||
| Number of sites | 12263 | 13715 | 13372 | 4847 | 6953 | |||||||||||||
| Total number of polymorphic sites | 40 | 213 | 82 | 32 | 161 | |||||||||||||
| Level of nucleotide diversity | Low | High | Medium | Medium | High | |||||||||||||
[i] Regions i–v correspond to Figure 1.
[ii] Ancestral haplotypes taken from Degli-Esposti et al. (1992).
[iii] The HLA alleles for the MHC ancestral haplotypes are as follows: 57.1 (HLA-A1; B57; DR7), 7.1 (HLA–A3; B7; DR15), 8.1 (HLA-A1; B8; DR3), 18.2 (HLA–A30; B18; DR3).
[iv] The Mann, Boleth, and CGM1 cell lines have been designated the MHC AHs 44.1, 62.1, 8.1 (one chromosome of the CGM1 cell line appears to contain the β block of the 8.1 AH), respectively.