Interphase FISH Screening for Low-Alphoid Cell Lines
| Chromosome | Chromosome-specific α-satellite probes | No. of cell lines | No. of low-alphoid centromeres | |||||
| phase I | phase II | total | phase I | phase II | total | prevalence[i] (%) | ||
| 1 | pZ5.1 | — | 328[ii] | 328[ii] | — | — | — | — |
| 2 | pX2 | 78 | 290 | 368 | — | — | — | — |
| 3 | pAE0.68 | 62 | 301 | 363 | — | — | — | — |
| 4 | p4n1/4 | 74 | 243 | 317 | — | — | — | — |
| 5 | pZ5.1 | — | 328[ii] | 328[ii] | — | — | — | — |
| 6 | pEDZ6 | 76 | 245 | 321 | — | — | — | — |
| 7 | pZ7.5 | 77 | 319 | 396 | — | — | — | — |
| 8 | pZ8.4 | 76 | 227 | 303 | — | — | — | — |
| 9 | pMR9A | 65 | 320 | 385 | — | — | — | — |
| 10 | pZ10-2.3 | 70 | 266 | 336 | — | — | — | — |
| 11 | Oncor D11Z1 | 76 | 312 | 388 | — | — | — | — |
| 12 | pB12 | 78 | 306 | 384 | — | — | — | — |
| 13 | αRI | 53 | 366 | 419 | — | 1 | 1 | 0.12 |
| 14 | αXT | 73 | 321 | 394 | — | — | — | — |
| 15 | pTRA20 | 58 | 328 | 386 | — | — | — | — |
| 16 | pZ16A-2 | 67 | 241 | 308 | — | — | — | — |
| 17 | TR17 | 78 | 357 | 435 | — | 1 | 1 | 0.11 |
| 18 | L1.84 | 69 | 239 | 308 | — | — | — | — |
| 19 | pZ5.1 | — | 328[ii] | 328[ii] | — | — | — | — |
| 20 | pZ20 | 77 | 268 | 345 | — | — | — | — |
| 21 | αRI | 53 | 366 | 419 | 6 | 25 | 31 | 3.70 |
| 22 | αXT | 73 | 321 | 394 | — | — | — | — |
| XY | XY α-mix[iii] | 67 | 294 | 361 | — | — | — | — |
[i] Prevalence is expressed in terms of the total number of chromosomes.
[ii] For chromosomes 1, 5 and 19, screening for low-alphoid centromeres was done on metaphase chromosomes.
[iii] This mix contains the X- and Y-specific probes, pLAX and pLAY5.5, respectively.