Expression Analysis of TUs
| TU | Size (kb) | Tissue specificity | Representation in tissue-specific cDNA libraries[i] |
| TU1 (DDB1) | 4.2 | all tissues tested, with higher expression in retina[ii] | placenta, fetal heart, fetal liver/spleen, fibroblast, fetal lung, blood peripheral lymphocytes, ovary, breast, brain |
| TU2 | 2.8 | lung, ARPE-19[ii] | melanocyte, fetal heart, infant brain, pregnant uterus, HeLa, placenta, uterus tumor, total fetus, endothelial cell, ovary tumor |
| TU3 | 1.3 | all tissues tested, with higher expression in retina[ii] | e.g., melanocyte, placenta, breast, fetal heart, pregnant uterus, fetal liver/spleen, retina, fetal heart, fetal cochlea, fetal lung |
| TU4 | 1.1 | all tissues tested[ii] | fetal liver/spleen, fetal heart, infant and adult brain, melanocyte, thyroid, fetal lung, embryo |
| TU5 | 4.0 | all tissues tested, with higher expression in lung[ii] , [iii] | infant brain |
| TU6 | 1.9 | all tissues tested[ii] | fetal liver/spleen |
| TU7 | 1.4 | all tissues tested[ii] | placenta, fetal liver/spleen, brain, melanocyte, multiple sclerosis lesions, fetal heart |
| TU8 | 7.5 | brain | infant brain |
| 7.0 | brain, liver, pancreas, placeta | ||
| 5.5 | placenta[iii] | ||
| TU9 | 7.5 | placenta, skeletal muscle, kidney[ii] , [iii] | retina |
| TU10 | 5.7 | lung, ARPE-19, with higher expression in ARPE-19[ii] | infant and adult brain, multiple sclerosis lesions, colon carcinoma, ovary tumor, cerebellum, hippocampus |
| TU11 (FEN1) | 2.3 | all tissues tested[ii] | infant brain, fetal liver/spleen, placenta, heart |
| TU12 | 4.0 | all tissues tested, with higher expression in ARPE-19[ii] | brain, fetal heart, fetal liver/spleen, neuroepithelium, melanocyte |
| TU13 | 4.0 | lung, cerebellum, retina | fetal/liver spleen, infant brain |
| 3.1 | cerebellum, retina, ARPE-19[ii] | ||
| TU14 (FTH1) | 1.1 | all tissues tested[ii] | lung, HeLa, fetal heart, placenta, fetal liver/spleen, fetal lung, endothelial, fetal spleen, pancreatic islets, brain |
| TU15 | 3.5 | lung, ARPE-19[ii] | fetal liver/spleen, pancreas tumor, retina |
| TU16 | 1.1 | all tissues tested[ii] | fetal liver/spleen, colon, B cell, skeletal muscle, lung |
| TU17 | 1.6 | all tissues tested[ii] | — |
[i] Data have been obtained from BLAST searches against dbEST and/or from the UniGene server at http:/www.ncbi.nlm.gov/UniGene/index.html
[ii] Lung, cerebellum, retina, ARPE-19 (total RNA blot).
[iii] Heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas [poly(A)+ RNA blot, Clontech].