Human GIP SNP rs2291725 exhibits a high population differentiation characteristic in the International HapMap II Project data set

[i] Genotypes were analyzed as described using the SPSmart v3 and Haplotter (Voight et al. 2006; Amigo et al. 2008). The average frequency of two alleles—derived allele GIP103C and ancestral chimpanzee allele GIP103T—at rs2291725 is approximately even in the overall HapMap population: Only 5.0% of YRI chromosomes contain GIP103C compared with 48.3% and 75.5% of CEU and ASN chromosomes that carry the derived allele, respectively.
[ii] aP < 0.05.