Table 1.

Overrepresented mismatches in mature miRNA sequences

257tbl1

[i] This table shows all overrepresented mismatches found in mature miRNAs before and after correcting for cross-mapping, except those occurring at the 3′ terminal nucleotide of the mature miRNA, together with the corresponding sequence counts, statistical significance after Bonferroni correction (see Methods), and the origin of cross-mapping RNAs if applicable. Before correcting for cross-mapping, 10 such potential miRNA editing sites are found. As shown in this table, eight of these are due to cross-mapping; one additional apparent editing site is due to a single nucleotide polymorphism in the THP-1 genome. The remaining editing site, in the mature miR-376c, has been identified previously (Kawahara et al. 2007a).