Table 1.
Penetrance and genotype relative risk (GRR) of two mutations in CYP6P9b and CYP6P4a strongly associated with pyrethroid resistance in An. funestus
[i] The parameters f0, f1, and f2 are the probabilities of being resistant in individuals with zero, one, and two copies of the resistant allele (G allele for both CYP6P4 and CYP6P9), respectively, while r2 and r1 are a quantification of the risk for a mosquito to be resistant if it is homozygous at the resistance locus (G/G for both genes) or heterozygous (A/G for both genes), respectively, compared with a susceptible mosquito (A/A at both genes).
[ii] Sus, susceptible; Res, resistant.