[i] ^aNumber of amino acids in the D. melanogaster protein.

[ii] ^bPercentage of the D. melanogaster codons used for the ω estimations (the rest represent positions poorly alignable or with alignment gaps).

[iii] ^cThe d_N and d_S values correspond to the sums across all branches of the melanogaster group phylogeny.

[iv] ^dNumber of PPIs involving each D. melanogaster protein.

[v] ^emRNA signal level in D. melanogaster adults (Chintapalli et al. 2007).

[vi] ^fParalogous genes encoding the eukaryotic initiation factor 4E (eIF4E).