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Table 1.

Level of coexpression (correlation coefficient of microarray datar ± standard error) for neighbouring genes in operons, on the same strand, on opposing strands, and for random gene pairs

		All genes		Exc. duplicate pairs		P
		N	r	N	r	P
Operons	1058	0.229 ± 0.007	747	0.210 ± 0.008	0.033
<500 bp on the same strand	1105	0.143 ± 0.007	586	0.097 ± 0.008	8 × 10⁻⁶
<500 bp on opposing strands	2091	0.128 ± 0.005	1513	0.116 ± 0.006	0.053
Random pairs	10,000	0.006 ± 0.002	10,000	0.001 ± 0.002	0.011

[i] The P values (for the difference between all gene pairs and gene pairs exc. duplicates) are from one-sided t-tests (significance at 0.05/4 = 0.013).