Genetic Polymorphisms in the RAS Genes, Whites and Blacks
| Polymorphism[i] (minor allele) | dbSNP[ii] | Whites | Blacks | δc | |||||
| minor allele freq. | HWE P value | minor allele freq. | HWE P value | ||||||
| REN | |||||||||
| C-4021T (T) | 0.12 | 0.24 | 0.28 | 0.29 | 0.16 | ||||
| C-3212T (T) | 0.08 | 0.07 | 0.13 | 0.06 | 0.05 | ||||
| A4280C (C) | rs5705 | 0.12 | 1.0 | 0.30 | 0.08 | 0.18 | |||
| G5795T (G) | rs5707 | 0.25 | 0.28 | 0.30 | 0.58 | 0.05 | |||
| C10377T (T) | 0.12 | 0.23 | 0.18 | 0.63 | 0.06 | ||||
| AGTR1 | |||||||||
| A-777T (A) | rs275651 | 0.14 | 1.0 | 0.31 | 0.86 | 0.17 | |||
| G-680T (G) | rs275652 | 0.14 | 0.2 | 0.26 | 0.18 | 0.12 | |||
| A-119G (G) | rs275653 | 0.15 | 0.35 | 0.26 | 0.14 | 0.11 | |||
| C43732T (T) | rs5182 | 0.50 | 0.64 | 0.21 | 0.07 | 0.29 | |||
| A44221G (G) | rs5183 | 0.05 | 1.0 | 0.33 | 0.32 | 0.28 | |||
| AGT | |||||||||
| C-532T (T) | rs5046 | 0.12 | 0.23 | 0.11 | 1.0 | 0.01 | |||
| A-217G (A) | rs5049 | 0.13 | 0.27 | 0.26 | 0.85 | 0.13 | |||
| A-6G (A) | rs5051 | 0.48 | 0.12 | 0.84 | 0.80 | 0.36 | |||
| C3889T (C) | rs4762 | 0.11 | 1.0 | 0.09 | 0.64 | 0.02 | |||
| C4072T (T) | rs699 | 0.48 | 0.71 | 0.15 | 0.36 | 0.33 | |||
| ACE | |||||||||
| A-239T (T) | rs4291 | 0.47 | 0.42 | 0.34 | 0.26 | 0.13 | |||
| A7941G (G) | rs4318 | 0.05 | 0.001 | 0.20 | 0.11 | 0.15 | |||
| C8342T (C) | rs4321 | 0.39 | 0.87 | 0.38 | 0.74 | 0.01 | |||
| A10539G (A) | rs4335 | 0.40 | 0.52 | 0.74 | 1.0 | 0.34 | |||
| A11599G (A) | rs4343 | 0.42 | 0.42 | 0.73 | 0.86 | 0.31 | |||
| A12292G (A) | rs4344 | 0.38 | 1.0 | 0.37 | 0.21 | 0.01 | |||
| A15990G (G) | rs4353 | 0.39 | 0.86 | 0.35 | 0.44 | 0.04 | |||
| C17911T (C) | rs4359 | 0.38 | 0.74 | 0.55 | 0.87 | 0.17 | |||
| C19329T (C) | rs4362 | 0.40 | 0.002 | 0.54 | 0.65 | 0.14 | |||
| A20060G (A) | rs4363 | 0.39 | 1.0 | 0.55 | 0.56 | 0.16 | |||
[i] Name given based on the position relative to exon 1 according to NCBI build number 30.
[ii] SNP ID in database dbSNP.