Comparison of the Results of Selected Signed Fisher Exact Test Analyses from Experiment 1
| Pathway | T1 | T2 | T3 | T4 | T5 | T6 | T7 |
| Oxidative phosphorylation map190 | 1.00 | 1.00 | 0.10 | 0.06 | 0.00 | 0.00 | 0.00 |
| Citrate cycle (TCA cycle) map20 | 1.00 | 1.00 | 1.00 | 0.05 | 0.03 | 0.00 | 0.00 |
| Electron Transport System, Complex II map3150 | 1.00 | 1.00 | 1.00 | 0.02 | 0.00 | 0.00 | 0.00 |
| Electron Transport System, Complex IV map3130 | 1.00 | 1.00 | 1.00 | 1.00 | 0.00 | 0.00 | 0.00 |
| Pyruvate metabolism map620 | 1.00 | 1.00 | 0.00 | 0.01 | 0.04 | 0.03 | 0.00 |
| Pentose phosphate cycle map30 | 1.00 | 1.00 | 0.07 | 1.00 | 0.03 | 0.00 | 0.00 |
| Reductive carboxylate cycle (CO2 fixation) map720 | 1.00 | 1.00 | 1.00 | 0.06 | 0.12 | 0.00 | 0.00 |
| Carbon fixation map710 | 1.00 | 1.00 | 0.04 | 0.13 | 0.07 | 0.12 | 0.00 |
| Glyoxylate and dicarboxylate metabolism map630 | 1.00 | 1.00 | 1.00 | 0.11 | 0.05 | 0.07 | 0.00 |
| ATP Synthase map3110 | 1.00 | 1.00 | 0.01 | 1.00 | 0.38 | 0.05 | 0.00 |
| Electron Transport System, Complex III map3140 | 1.00 | 1.00 | 1.00 | 0.03 | 1.00 | 0.00 | 0.01 |
| Glycolysis/Gluconeogenesis map10 | 1.00 | 1.00 | 0.01 | 0.16 | 0.06 | 0.49 | 0.01 |
| Alanine and aspartate metabolism map252 | 1.00 | 1.00 | 0.00 | 0.26 | 0.19 | −0.22 | 0.02 |
| beta-Alanine metabolism map410 | 1.00 | 1.00 | 1.00 | 0.00 | 0.01 | 0.15 | 0.07 |
| Glutamate metabolism map251 | 1.00 | 1.00 | 0.08 | 0.01 | −0.05 | −0.16 | 0.07 |
| Butanoate metabolism map650 | 1.00 | 1.00 | 0.10 | 0.02 | 0.07 | 0.07 | 0.07 |
| Taurine and hypotaurine metabolism map430 | 1.00 | 1.00 | 1.00 | 1.00 | 0.00 | 0.06 | 0.07 |
| Prostaglandin and leukotriene metabolism map590 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.06 | 0.07 |
| Fructose and mannose metabolism map51 | 1.00 | 1.00 | 1.00 | 0.03 | 0.59 | 0.53 | 0.09 |
| Fatty acid metabolism map71 | 1.00 | 1.00 | 1.00 | 0.13 | 0.07 | −0.26 | −0.09 |
| Glutathione metabolism map480 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.10 | 0.11 |
| Cysteine metabolism map272 | 1.00 | 1.00 | 1.00 | 1.00 | −0.01 | −0.46 | −0.11 |
| Glycine, serine and threonine metabolism map260 | 1.00 | 1.00 | 0.17 | 0.43 | 0.07 | −0.10 | −0.08 |
| Synthesis and degradation of ketone bodies map72 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | −0.07 |
| Pantothenate and CoA biosynthesis map770 | 1.00 | 1.00 | 1.00 | −0.04 | −0.08 | −0.15 | −0.07 |
| Valine, leucine and isoleucine biosynthesis map290 | 1.00 | 1.00 | 0.04 | −0.11 | −0.21 | −0.07 | −0.04 |
| Selenoamino acid metabolism map450 | 1.00 | 1.00 | 1.00 | 1.00 | 0.00 | −0.02 | −0.01 |
| Methionine metabolism map271 | 1.00 | 1.00 | 1.00 | 1.00 | −0.01 | −0.03 | 0.00 |
| Aminoacryl-tRNA biosynthesis map970 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.00 | 0.00 |
| RNA polymerase map3020 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | −0.12 | 0.00 |
| Pyrimidine metabolism map240 | 1.00 | 1.00 | 1.00 | 1.00 | −0.53 | −0.17 | 0.00 |
| Purine metabolism map230 | 1.00 | 1.00 | 0.01 | −0.82 | 0.09 | −0.03 | 0.00 |
| Ribosome map3010 | 1.00 | 1.00 | 1.00 | 1.00 | −0.99 | 0.00 | 0.00 |
[i] (T0 vs T1) to 7 (T0T7) (T1 = 9 hours, T2 = 11 hours, T3 = 13 hours, T4 = 15 hours, T5 = 17 hours, T6 = 19 hours, T7 = 21 hours) The results have been sorted according to their ranking in the T7 column. The table shows only pathways with an absolute P-value of the Fisher exact test greater than or equal to 0.1; the complete results are reported in Supplementary material, Table 2.xls.