Protein Families Found in the Dense Region of the Cloud in Figure3
| Family | Dom. | Class | Spec. | Definition |
| HBG000224 | 1 | info | 31 | NAD-dependent DNA ligase family |
| HBG000226 | 1 | info | 28 | DNA polymerase III α chain |
| HBG000253 | 1 | info | 31 | EF-Ts family |
| HBG000387 | 2 | info | 19 | Glutamyl-tRNA reductase family |
| HBG000436 | 1 | info | 28 | Translation initiation factor IF-1 |
| HBG000440 | 3 | info | 39 | Translation initiation factor IF-2 |
| HBG000445 | 1 | info | 31 | Translation initiation factor IF-3 |
| HBG000531 | 1 | info | 23 | Transcriptional-repair coupling factor |
| HBG000910 | 1 | info | 30 | S5P family of ribosomal proteins |
| HBG003694 | 1 | info | 29 | Excinuclease ABC subunit C UvrC family |
| HBG005458 | 3 | info | 42 | 30S ribosomal protein S10P |
| HBG006229 | 1 | info | 28 | tRNA δ(2)-isopentenylpyrophosphate transferase |
| HBG008973 | 2 | info | 41 | Alanyl-tRNA synthetase |
| HBG008994 | 1 | info | 30 | Leucyl-tRNA synthetase |
| HBG009221 | 2 | info | 33 | Threonyl-tRNA synthetase |
| HBG010120 | 1 | info | 25 | DNA repair protein RadA |
| HBG011587 | 3 | info | 45 | S7P family of ribosomal proteins |
| HBG011828 | 3 | info | 44 | 30S ribosomal protein S3P |
| HBG011949 | 1 | info | 28 | 50S ribosomal protein L17 |
| HBG012008 | 1 | info | 30 | S15P family of ribosomal proteins |
| HBG012054 | 1 | info | 32 | Peptidyl-tRNA hydrolase Pth family |
| HBG012248 | 1 | info | 32 | L20P family of ribosomal proteins |
| HBG012249 | 1 | info | 29 | Phenylalanyl-tRNA synthetase α chain |
| HBG012416 | 2 | info | 39 | Valyl-tRNA synthetase |
| HBG012497 | 3 | info | 43 | L6P family of ribosomal proteins |
| HBG012522 | 1 | info | 26 | Phenylalanyl-tRNA synthetase β chain |
| HBG012593 | 3 | info | 43 | 50S ribosomal protein L1P |
| HBG012594 | 1 | info | 30 | DNA-directed RNA polymerase β chain |
| HBG012618 | 3 | info | 44 | S2P family of ribosomal proteins |
| HBG012650 | 1 | info | 15 | Ribosomal protein L11 methyltransferase |
| HBG013445 | 1 | info | 31 | L19P family of ribosomal proteins |
| HBG013652 | 1 | info | 31 | Ribosome releasing factor RRF family |
| HBG013954 | 1 | info | 22 | DNA repair and genetic recombination protein RecN |
| HBG014295 | 1 | info | 30 | Holliday junction DNA helicase RuvB |
| HBG014467 | 1 | info | 28 | DNA-directed RNA polymerase β′ chain |
| HBG014469 | 3 | info | 42 | L11P family of ribosomal proteins |
| HBG014584 | 1 | info | 29 | DNA-directed RNA polymerase α chain |
| HBG014585 | 3 | info | 44 | 50S ribosomal protein 15P |
| HBG014588 | 1 | info | 31 | 50S ribosomal protein L16 |
| HBG014596 | 1 | info | 32 | Aspartyl-tRNA synthetase |
| HBG014727 | 3 | info | 42 | Seryl-tRNA synthetase |
| HBG015438 | 1 | info | 14 | EF-1 for elongation factor 1-α |
| HBG016715 | 1 | info | 25 | RecG subfamily of helicases |
| HBG016735 | 1 | info | 31 | L18P family of ribosomal proteins |
| HBG016737 | 1 | info | 30 | L22P family of ribosomal proteins |
| HBG016768 | 1 | info | 31 | L4P family of ribosomal proteins |
| HBG016876 | 1 | info | 31 | tRNA methyltransferase |
| HBG018696 | 1 | info | 25 | DNA polymase type-A family PolA |
| HBG019433 | 2 | info | 18 | DNA mismatch repair MutL/HexB family |
| HBG020375 | 1 | info | 19 | A/G-specific adenine glycosylase MutY |
| HBG057220 | 1 | info | 25 | Prolyl-tRNA synthetase |
| HBG000042 | 2 | oper | 24 | Adenine phosphoribosyltransferase |
| HBG000063 | 1 | oper | 24 | ATP synthase α chain |
| HBG000069 | 1 | oper | 24 | ATPase γ chain family |
| HBG000092 | 2 | oper | 20 | Biotin and lipoic acid synthetases family |
| HBG000137 | 1 | oper | 28 | ATP-dependent Clp protease |
| HBG000315 | 2 | oper | 13 | Ferritin-like protein |
| HBG000337 | 1 | oper | 21 | Riboflavin biosynthesis protein RibA |
| HBG000348 | 1 | oper | 14 | Glucose inhibited division protein B homolog GidB |
| HBG000379 | 1 | oper | 23 | GMP synthetase |
| HBG000380 | 2 | oper | 35 | GTP-binding protein Guf1 |
| HBG000388 | 3 | oper | 30 | Alanine dehydrogenase family |
| HBG000421 | 1 | oper | 10 | Hpr serine/threonine protein kinase PtsK family |
| HBG000471 | 2 | oper | 32 | Guanylate kinase Gmk protein |
| HBG000529 | 2 | oper | 31 | Adenosylmethionine synthetase family |
| HBG000560 | 1 | oper | 24 | UDP-N-acetylmuramoylalanine-D-glutamate ligase MutD |
| HBG000564 | 1 | oper | 25 | MurCDEF family |
| HBG000595 | 1 | oper | 28 | N utilization substance protein A homolog |
| HBG001251 | 1 | oper | 32 | UPF0117 family unknown function |
| HBG001398 | 1 | oper | 24 | Menaquinone biosynthesis methyltransferase |
| HBG001475 | 1 | oper | 21 | GTP-binding protein TypA/BipA homolog |
| HBG001546 | 1 | oper | 12 | Flagella basal body Rod proteins family |
| HBG001832 | 1 | oper | 21 | Unknown function |
| HBG002257 | 2 | oper | 20 | Stationary-phase survival protein SurE |
| HBG002555 | 1 | oper | 14 | CysE/LacA/LpxA/NodL family of acetyltransferases |
| HBG002569 | 1 | oper | 15 | 3-deoxy-manno-octulosonate cytidylyltransferase |
| HBG002592 | 1 | oper | 22 | Exodeoxyribonuclease VII large subunit |
| HBG002674 | 1 | oper | 20 | HemK protein homolog |
| HBG002766 | 1 | oper | 17 | Heat shock protein HsIV |
| HBG002767 | 1 | oper | 17 | ATP-dependent Hsl protease |
| HBG002854 | 2 | oper | 32 | GatB family |
| HBG002953 | 2 | oper | 28 | UPF0038 family unknown function |
| HBG003029 | 2 | oper | 29 | Glycerol-3-phosphate dehydrogenase [NAD+] |
| HBG003087 | 1 | oper | 16 | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase |
| HBG003095 | 2 | oper | 22 | Scc-independent protein translocase protein TalC |
| HBG003169 | 1 | oper | 27 | Guanosine pentaphosphate synthetase |
| HBG003178 | 1 | oper | 26 | Unknown function |
| HBG003219 | 1 | oper | 31 | Preprotein translocase SecY subunit |
| HBG003373 | 1 | oper | 14 | Penicillin-binding protein Pbp2 |
| HBG004350 | 2 | oper | 27 | Phosphoribosylamine—glycine ligase |
| HBG005358 | 2 | oper | 34 | Protease Qri7 |
| HBG005857 | 2 | oper | 16 | Unknown function |
| HBG006494 | 1 | oper | 15 | Unknown function |
| HBG006702 | 1 | oper | 12 | Bacteriocin gene regulator Hfq protein |
| HBG007038 | 1 | oper | 23 | Unknown function |
| HBG007596 | 1 | oper | 10 | Flagellar protein FliS |
| HBG007971 | 1 | oper | 19 | Fpg family |
| HBG008259 | 1 | oper | 16 | UPF0040 family unknown function |
| HBG008387 | 1 | oper | 16 | UPF0088 family unknown function |
| HBG008920 | 1 | oper | 27 | Cytidylate kinase family |
| HBG008981 | 3 | oper | 44 | GTP-binding protein Gtp1/Obg family |
| HBG009096 | 1 | oper | 15 | Unknown function |
| HBG009213 | 1 | oper | 16 | Unknown function |
| HBG009256 | 1 | oper | 16 | General stress protein Ctc |
| HBG009692 | 1 | oper | 18 | Unknown function |
| HBG011361 | 2 | oper | 25 | GTP-binding protein HflX |
| HBG012031 | 1 | oper | 32 | SmpB protein family |
| HBG012163 | 1 | oper | 12 | Flagellar protein FLiG |
| HBG012209 | 1 | oper | 23 | MurCDEF family |
| HBG012397 | 1 | oper | 19 | PhoH family |
| HBG013158 | 1 | oper | 27 | RNAse III family |
| HBG014707 | 2 | oper | 39 | Phosphoglycerate kinase |
| HBG016560 | 1 | oper | 13 | Phosphoglyceromutase |
| HBG016999 | 1 | oper | 29 | UPF0011 family unknown function |
| HBG017494 | 1 | oper | 15 | Unknown function |
| HBG024417 | 1 | oper | 10 | Phosphate acetyltransferase |
| HBG033861 | 2 | oper | 16 | UPF0044 family unknown function |
| HBG042814 | 1 | oper | 26 | CDP-alcohol phosphatidyltransferase class-I family |
| HBG057111 | 2 | oper | 13 | GTP-binding protein Gtp1/Obg family |
| HBG057805 | 1 | oper | 25 | MurCDEF family |
| HBG070402 | 1 | oper | 27 | GTP-binding protein Era |
[i] Family, HOBACGEN-CC family number; Dom., number of domains (i.e., Bateria, Archaea, and Eukarya) represented in the family; Spec., number of species represented in the family; Definition, simplified HOBACGEN-CG description of the family.