Table 1.

Distribution of the Different Genotypes at the ThreeEcl-loci in 91 Circling and 47 Noncircling Mice

No. of risk alleles Ecla (chrom 3) Eclb (chrom 4) Eclc (chrom 13) No. of circling mice (% animals) No. of noncircling mice (% animals)
6AABBCC11 (12)1 (2)
5AaBBCC14 (15)1 (2)
AABBCc12 (13)1 (2)
AABbCC7 (7)2 (4)
4AaBbCC11 (12)2 (4)
AaBBCc10 (10)2 (4)
AABbCc4 (4)0 (0)
AABBcc3 (3)2 (4)
aaBBCC3 (3)1 (2)
AAbbCC0 (0)0 (0)
3aaBbCC4 (4)2 (4)
aaBBCc3 (3)1 (2)
AaBbCc3 (3)4 (8.5)
AABbcc2 (2)4 (8.5)
AaBBcc1 (1)4 (8.5)
AAbbCc0 (0)4 (8.5)
AabbCc0 (0)0 (0)
2AAbbcc1 (1)[ii] 1 (2)
AaBbcc1 (1)0 (0)
aaBBcc1 (1)3 (6)
aaBbCc0 (0)4 (8.5)
AabbCc0 (0)3 (6)
aabbCC0 (0)1 (2)
1Aabbcc0 (0)3 (6)
aaBbcc0 (0)1 (2)
aabbCc0 (0)0 (0)
0aabbcc0 (0)0 (0)

[i] The noncircling mice represent a selected group that shows homozygosity for the recessive Ecs-gene. Upper cases represent risk-alleles derived from C57L/J and lower cases represent nonrisk alleles derived from SWR/J.

[ii] This is the single circling mouse that did not inherit a copy of the Eclb-risk allele for the neighboring marker. A recombination between the marker and the risk conferring mutation may have occurred in this animal.