Table 1.

Young Retroposed Genes in the Drosophila melanogasterGenome Compared to Its Parental Genes

# New genes Parental genes Gene type KA/Ks Ks
Locus Position Expression Locus Position Expression
1 CG12628 2L_40D— Mgst1 X_19E GH/LPGlutathion transferase0.53700.03015
2 CG12324 2R_47CLP RpS15A X_11E AT/GMRibosomal protein0.24880.04035
3 CG10174 2L_36Fat Dntf2 X_19E GH/LPTransporter0.34260.16811
4 CG13732 3L_74Cat CG15645 X_13E aUnknown0.79510.19015
5 CG4960 3R_96FAT CG8331 2R_50EGM/GH/LPMembrane protein 0.3630 0.32681
6 Act5C X_5CLD/LP/GH Act57B 2R_57BAT/GM/HLActin 0.0744 0.33619
7 CG17856 3R_98Cat CG3560 X_14B GH/LPNAD dehydrogenase 0.1767 0.67448
8 CG11825 2R_47A— CG17734 3R_86DLPUnknown 0.1691 0.73976
9 CG12334 3R_90CAT CG1534 X_9E GM/LP/LDUnknown 0.1405 0.73999
10 Act42A 2R_42AAT Act79B 3L_79BGH/LPActin 0.0400 0.74529
11 Vha36 2R_52AAT/GM/GH CG8310 X_3A —Transporter 0.1583 0.80580
12 Trxr2 3L_79EAT Trxr1 X_7D AT/GM/LDGlutathion reductase 0.2102 0.89926
13 CG7768 3L_70DAT Cyp33 2R_54CLDChaperone 0.2940 0.90764
14 Ef1α48E 2R_48DLD/HL/SD Ef1α100E 3R_100EHL/LPTranslation Ef. 0.0654 0.91664
15 CG7235 2L_25FAT/GH Hsp60 X_10A AT/GM/LDChaperone 0.1362 0.92378
16 Pros28.1A 3R_92FAT/LP Pros28.1 X_14B LDEndopeptidase 0.1637 0.95103
17 CanB X_4Fat/gdm CanB2 2R_43ESDProtein phosphatase 0.0177 1.03241
18 CG9819 X_14FLP CanA1 3R_100BGHProtein phosphatase 0.1007 1.16483
19 CG9873 2R_59Cat CG9091 X_13B GM/SD/LPRibosomal protein 0.1693 1.22348
20 Sep5 2R_43FLD Sep2 3R_92EGM/LD/SDCytoskeletal protein 0.1647 1.23927
21 CG13340 2R_50CAT CG8040 3L_67DAT/GH/LPPeptidase 0.1256 1.31892
22 Cdlc2 2L_22AAT/GH/LP ctp X_4C AT/GM/LPDynein light chain 0.0030 1.43721
23 CG4706 3R_86DAT Acon 2L_39BGM/LD/HLAconitase 0.0789 1.52027
24 CG8602 3L_65FGH/LD/SD CG12194 2L_25B—Sugar transporter 0.1099 1.56227

[i] This is a subsample of young retroposed copies whose parental gene lies in a different chromosome (see text for details). TheKA/KS ratio is in bold when it is significantly smaller than 0.5. We have checked expression experimentally for some genes in adult males and females (a), gonadectomized males (gdm), and testis (at) (see Fig. 1 for details) and used information from Berkeley Drosophila Genome Project (BDGP) EST libraries for the other genes. Tissues in this latter case are named following BDGP nonmenclature: LD (embryos), LP (larvae and early pupae), HL and GH (both adult heads), SD (Schneider L2 cells), AT (adult testis), and GM (ovaries). When the gene is expressed in more than three tissues, only the three in which the gene is most highly expressed or more relevant for discussion, i.e., AT and GM, have been listed. The lowercase letters indicate the data from our expression experiments, and the uppercase letters the data from the BDGP EST library.