Table 1.

B6.129-KO Strains Currently Commercially Available from the Jackson Laboratory (2001)

Strain Chr Position
B6.129S7-Il1r1tm11mx 119.1
B6.129S2-Cd28tm1Mak 130.1
B10.129P2(B6)-Il10tm1Cgn 169.9
B6.129S7-Selptm1Bay 186.6
B6.129S4-Cd3ztm1Lov 187.2
B6.129P2-Fcgr3tm1Sjv 192.3
B6.129P2-B2mtm1Unc 269
B6.129P2-Tnfrsf5tm1Kik 297
B6.129S1-Il12atm1Jm 337
B6.129-Tnfrsf1btm1Mwm 475.5
B6.129P2-Nos3tm1Unc 59
B6.129S6-Il6tm1Kopf 517
B6.129S7-Ldlrtm1Her 520
B6.129P2-Tcrbtm1Mom 620.5
B6.129S1-Il12rb2tm1Jm 630.1
B6.129S2-Cd8atm1Mak 630.5
B6.129S7-Gtrosa26 648.7
B6.129S7-Gtrosa26tmSho 648.7
B6.129S7-Gtrosa26tmSor 648.7
B6.129S2-Cd4tm1Mak 660.2
B6.129S6-Cd4tm1Knw 660.2
B6.129-Tnfrsf1atm1Mak 660.5
B6.129S4-Nft3tm2Jae 661
B6.129-Cdkn1btm1Mlf 662
B6.129P2-Apoetm1Unc 74
B6.129S7-Chrna7tm1Bay 730
B6.129S2-Plattml 89
B6.129S7-LdlrtmlHer 95
B6.129S4-Icam1tm1Jcgr 97
B6.129S7-Icamltm1Bay 97
B6.129P2-Apoa1tm1Unc 927
B6.129P2-Lipctm1Unc 939
B6.129S1-Grik2tm1Sfh 1027
B6.129S7-Itgb2tm1Bay 1041.5
B6.129S7-Ifngtm1Ts 1067
B6.129-Il12btm1Jm 1119
B6.129-Il2rgtm1Wjl 1129
B6.129P2-Il4tm1Cgn 1129
B6.129S2-Alox15tm1Fun 1140
B6.129P2-Lipctm1Unc 1145.6
B6.129P2-Scya3tm1Unc 1147.6
B6.129S4-Ngfrtm1Jae 1155.6
B6.129P2-Apobtm1Unc 122
B6.129-Ahrtm1Bra 1218
B6.129S2-Igh-6tm1Cgn 1258
B6.129P2-Agtr1atm1Unc 1316
B6.129P2-Tcrdtm1Mom 1419.5
B6.129S2-Tcratm1Mom 1419.5
B6.129S7-I17rtm1Imx 154.6
B6.129S4-Cd86tm1Shr 1626.9
B6.129S4-Cd80tm1Shr 1628
B6.129P2-Plgtm1 177.3
B6.129S2-Ltatm1Dch 1719.1
B6.129S4-C3tm1Crr 1734.3
B6.129S-Cd14tm1Frm 1831
B6.129S6-Iltm1Liz 1832
B6.129S2-Tnfsf5tm11mx X18
B6.129P2-Fmr1tm1Cgr X24.5
B6.129-Il2rgtm1Wjl X38

[i] This list excludes knockouts that are cryopreserved, difficult to breed, severely immunodeficient, or homozygous lethal. There may be additional issues related to using some of these strains. In addition to the 59 strains listed, the Jackson Laboratory has 41 knockout strains in the process of being backcrossed to B6 and 74 strains which only exist as cryopreserved stocks. Many of the congenics are clustered and represent different knockouts of the same gene or different genes in gene clusters. These overlapping congenics were included because they will have considerable utility for fine mapping QTLs in the region.