Table 1.

General Comparative Features of thePyrococcus Genomes

Genome features P. abyssi P. horikoshii P. furiosus
Chromosome size (bp)1,765,1181,738,5051,908,253
Protein coding regions91.1%91.2%92.5%
G+C content44.7%41.9%40.8%
Stable RNAs
tRNAs464646
tRNAs with intronsTrp, MetTrp, MetTrp, Met
Ribosomals16S-23S,16S-23S,16S-23S,
 5Sa, 5Sb 5Sa, 5Sb, 5Sa, 5Sb
 7S 7S 7S
OthersRnase PRnase PRnase P
Open reading frames1,76520612208
Genes belonging to  families of paralogs621606845
Putative function assigned51%20%
 Informational genes14%
 Operational genes37%
Unknown function49%80%
Mobile elements
Inteins141410
Insertion Sequences1 vestigial IS1 vestigial IS24
Repeats#
LCTR R1 family130
LCTR R2 family337

[i] #LCTR are clusters of ∼30-bp-long tandem repeats separated by linkers ranging from 60 to 100 bp.

[ii] R1 family consensus: GTTTC-CGTAGAACNNANNAGTGTGGAAA

[iii] R2 family consensus: GTTNCANNAAGANNANAANAGAATTGAA