Gene Families Used in Phylogenetic Analyses
| Gene family | Abbreviation | Human proteins (Accession no.) [Chromosomal location of gene] |
| Acetylcholine receptor | ACHR | ACHRD (Q07001) [2], ACHRG (P07510) [2], ACHRB (P11230) [17], ACHRE (Q04844) [17] |
| Acetyl-coA carboxylase | COA2 (O00763) [12], COA1 (Q13085) [17] | |
| Actin | ACT | ACTH (P12178) [2], ACTB (P02570) [7], ACTG (P02571) [17] |
| Acyl-coA dehydrogenase | ACAD | ACAD-L (P28330) [2], ACAD-S (P16219) [12], ACAD-VL (P49748) [17], COA-OXP (Q15067) [17] |
| ADP-ribosylation factor | ARF | ARF5 (P26437) [7], ARF3 (P16587) [12], ARL6 (P49703) [17], ARL7 (P56559) [17] |
| Anion exchanger | AE | AE3 (P48751) [2], AE2 (P04920) [7], AE1 (P02730) [17] |
| Aquoporin | AQP | AQP1 (P29972) [7], AQP2 (P41181) [12] |
| Arrestin | ARR | S-ARR (P10523) [2], ARR2 (P32121) [17] |
| Brain amiloride-sensitive sodium channel | BNAC | BNA2 (U78181) [12], BNA1 (Q16515) [17] |
| Cyclin-dependent kinase | CDK | CDK7 (P50613) [2], CDK5 (Q00535) [7], CDK4 (P11802) [12], CDK3 (Q00526) [17] |
| Enolase | ENOL | ENOLG (P09104) [12], ENOLB (P13929) [17] |
| ERBB receptor protein-tyrosine kinase | ERBB | ERBB4 (Q15303) [2], EGFR (P00533) [7], MET (P08581) [7], ERBB3 (P21860) [12], ERBB2 (P04626) [17] |
| Even-skipped | EVX2 (Q03828) [2], EVX1 (P49640) [7] | |
| Frizzled | FR1 (AB017363) [2], FR7 (AB017365) [7] | |
| GLI zinc-finger protein | GLI | GLI2 (P10070) [2], GLI3 (P10071) [7], GLI1 (P08151) [12] |
| Glucagon | GCG | GCG (P01275) [2], GIP (P09681) [17] |
| Glucose transporter | GLUT | GLUT3 (P11169) [12], GLUT4 (P14672) [17] |
| G protein-coupled receptor | GPR | CCR4 (P30991) [2], IL8RA (P25024) [2], IL8RB (P25025) [2], NK-1R (P25103) [2], GPR37 (Y12476 {7], CKR7 (P32248) [17], SSR2 (P30874) [17] |
| Guanine nucleotide-binding protein | GNB | GNB2 (P11016) [7], GNB3 (P16520) [12] |
| Hedgehog | HH | IHH (Q14623) [2], SHH (Q15465) [7] |
| Hepatocyte nuclear factor | HNFA (P20823) [12], HNFB (P35680) [17] | |
| Immunoglobulin-related | IG | CD28 (P10747) [2], CTL4 (P16410) [2], CD4 (P01730) [12], CD7 (P09564) [17] |
| Inhibin | INHB | INHA (P05111) [2], INHBB (P09529) [2], INHBA (P08476) [7], INHBC (P55103) [12] |
| Insulin-like growth factor-binding protein | IGBP | IGBP2 (P18065) [2], IGBP1 (P08833) [7], IGBP3 (P17936) [7], IGBP4 (P22692) [17] |
| Integrin α | INTA | INTA4 (P13612) [2], INTA6 (P23229) [2], INTAV (P06756) [2], INTA5 (P08648) [12], INTA7 (AF032108) [12], INTAIIB (P08514) [17] |
| Integrin β | INTB | INTB6 (P18564) [2], INTB8 (P26012) [7], INTB7 (P26010) [12], INTB3 (P05106) [17] |
| Intermediate filament | IF | Desmin (P17661) [2], KRT1-18 (P05783) [12], KRT2-1 (P04264) [12], KRT2-2E (P35908) [12], KRT2-3 (PP12035) [12], KRT2-4 (P19013) [12], KRT2-5 (P13647) [12], KRT2-6A (P02538) [12], KRT2-7 (P08729) [12], KRT2-8 (P05787) [12], Peripherin (P41219) [12], KRT1-9 (P35527) [17], KRT1-10 (P13645) [17], KRT1-12 (Q99456) [17], KRT1-13 (P13646) {17], KRT1-14 (P02533) [17], KRT1-15 (P19012) [17], KRT1-16 (P30654) [17], KRT1-17 (Q04695) [17], KRT1-17-2 (P08779) [17], KRT1-19 (P08727) [17], KRT1-HA1 (Q15323) [17], KRT1-HA2 (Q14532) [17], KRT1-HA3 (Q14525) {17], KRT1-HA5 (Q92764) [17] |
| Myosin light chain | MYL1 (P05976) [2], MYL3 (P06741) [2], MYLE (P12829) [17] | |
| NAB transcriptional regulator | NAB1 (NM_005966) [2], NAB2 (U48361) [12] | |
| NRAMP | NRAMP1 (D50402) [2], NRAMP2 (L37347) [12] | |
| Nuclear hormone receptor | NHR | NOT2 (P43354) [2], RARG1 (P13631) [12], ESTR ;(P03372) [12], NOFIP (P22736) [12], VDR (P11473) [12], RARA1 (P10276) [17], THRA1 (P21205) [17], THRA2 (P10827[17] |
| Neurokinin | NKN | TAC1 (NM_012666) [7], TAC3 (NM_013251) [12] |
| Nitric oxide synthetase | NOS | NOS3 (P29474) [7], NOS1 (P29475) [12], NOS2 (P35228) [17] |
| Olfactory receptor | OR | OR7-10.3 (AC004853) [7], OR7-138 (U86278) [7], OR7-140 (U86280) [7], OR7-141 (U86281) [7], OR17-2 (P47882) [17], OR17-4 (U53583) [17], OR17-15 (U86244) [17], OR17-16 (U86245) [17], OR17-24 (P47883) [17], OR17-30 (U86240) [17], OR17-32 (P47885) [17], OR17-40 (U04683) [17], OR17-82 (P47886) [17], OR17-93 (U76377) [17], OR17-130 (U86240) [17], OR17-135 (U86241) [17], OR17-201 (U76377) [17], OR17-207 (P47889) [17], OR17-209 (U53583) [17], OR17-210 (U53583) [17], OR17-219 (P47892) [17], OR17-228 (P47893) [17] |
| Pancreatic polypeptide/ neuropeptide Y | Neuropeptide Y (P01303) [7], pancreatic polypeptide (P01298) [17] | |
| Peroxidase | TPO (P07202) [2], MPO (P05164) [17] | |
| Proteasome β subunit | PSMB | PSMBθ (P49720) [2], PSMBD (P28072) [17] |
| RAD52 | RAD52 | Ψ-RAD52 (U22171-U22172) [2], RAD52 (U12134) [12] |
| Ras-related | RASR | RAB1A (P11476) [2], RAB6 (P20340) [2], RALB (P11234) [2], RALA (P11233) [7], RAP1B (P09526) [12], RAB13 (P51153) [12], K-RAS2A (P01116) [12], K-RAS2B (P01118) [12] |
| Sodium channel | SCN | SCNA2 (Q99250) [2], SCNA6 (Q01118) [2], SCNA4 (P35499) [17] |
| Synapyobrevin | SYB | SYB1 (P23763) [12], SYB2 (P19065) [17] |
| Wnt-related | WNT | WNT2 (P09544) [7], WNT1 (P04628) [12], WNT10B (O00744) [12], WNT3 (A47536) [17] |