Table 1.

Variable Diallelic Loci Used in the Example Application

Locus Relative frequency[i] pv Location Reference
APOB 2p24
 InDel0.6830.000Exon 1 Boerwinkle and Chan 1989
 XbaI RFLP0.5250.002Exon 26 Berg et al. 1986
 MspI RFLP0.8990.009Exon 26 Priestley et al. 1985
 EcoRI RFLP0.8710.000Exon 29 Shoulders et al. 1985
PONl 7q22
 L54M0.6290.000Exon 3 Humbert et al. 1993
 R192N0.7180.010Exon 6 Humbert et al. 1993
LPL 8p22
 PvuII RFLP0.5260.000Intron 6 Li et al. 1988
 HindIII RFLP0.7210.012Intron 8 Heizmann et al. 1987
 BstNI RFLP0.7030.000Intron 9 Funke et al. 1988
APOAl-C3-A4 11q23
 InDel0.5480.0105′ of APOAl Coleman et al. 1986
 PstI RFLP0.9430.0103′ of APOAl Kessling et al. 1985
 SstI RFLP0.9070.000Exon 4, APOC3 Rees et al. 1983
LDLR 19p13
 TaqI RFLP0.9110.017Intron 4 Yamakawa et al. 1987
 StuI RFLP0.9550.021Exon 8 Kotze et al. 1986
 HincII RFLP0.5560.000Exon 12 Leitersdorf and Hobbs 1987
 AvaII RFLP0.5520.000Exon 13 Hobbs et al. 1987
APOE 19p13.2
 C112R0.8330.000Exon 4 Rall et al. 1982
 R158C0.9220.000Exon 4 Rall et al. 1982

[i] For the most common allele.

[ii] Loci are shown with the proportion of lnTrig variability (pv) that they explain independently.