Table 1.

Location of Sth QTL as Determined from the F2 Intercross

QTL Microsatelite marker cM LOD score (% explained) Avg % Expl
Day 15 Day 21 Day 25
Sth1D1MIT33449.26.95 (5.8)6.82 (5.6)7.06 (5.8)6.94
Sth2D3MIT21743.75.86 (7.0)6.18 (7.6)5.38 (6.5)7.0
Sth3D4MIT21421.96.48 (5.7)7.26 (6.4)6.14 (5.4)6.6
Sth4D4MIT3150.35.30 (5.5)6.82 (6.2)6.50 (6.0)6.2
Sth5D6MIT26129.53.60 (3.2)4.50 (4.0)4.11 (3.7)4.07
Sth6[ii] D7MIT22038.33.05 (2.9) (S)4.36 (4.1)4.84 (4.8)4.08
Sth7D7MIT1262.33.54 (3.1)3.84 (3.6)4.26 (3.9)3.88
Sth8D9MIT20731.711.99 (10.2)13.95 (11.8)14.18 (12.0)13.54
Sth9D9MIT27041.512.99 (10.8)15.60 (13.0)16.11 (13.3)14.90
Sth10[ii] D13MIT22845.92.92 (2.5)(S)3.03 (2.6)(S)2.72 (2.4)(S)2.89

[i] The LOD threshold determined by permutation test is ≥3.5 for significant linkage and 2.7 for suggestive linkage (the same as significant level of 1% and 5%, respectively) for a chromosome length of 100 cM.

[ii] QTLs identified previously by McBrearty et al. (1998).

[iii] Avg % Exp = Average (days 15, 21, and 25) percent variance explained F2 mice (70%).