χ2-Statistical Analysis of Three Independent Whole-Genome Transcription Profiles
| Genomewide protein-protein interaction database | Genomewide transcription profiles | χ2 | P-value |
| UETZ | CC | 16.6 | 4.7*10−05 |
| PHE | 11.8 | 6.0*10−04 | |
| SPO | 17.3 | 3.2*10−05 | |
| ITO-core | CC | 10.0 | 1.6*10−03 |
| PHE | 7.8 | 5.3*10−03 | |
| SPO | 12.1 | 5.0*10−04 | |
| ITO-full | CC | 52.0 | 5.5*10−13 |
| PHE | 51.2 | 8.0*10−13 | |
| SPO | 55.0 | 1.2*10−13 |
[i] χ2-statistical analysis of three independent whole genome transcription profiles—cell cycle (CC), response to pheromone (PHE), and sporulation (SPO)—reveals that there is a significantly higher fraction of positively correlated transcription of protein-protein interactions in the MIPS database compared to the protein-protein interactions of the whole-genome screens (UETZ, ITO-core, ITO-full).